Gene View
| Gene Information |
| NCBI Gene ID: 317 |
Organism: Homo sapiens |
| Gene Symbol: APAF1 |
Chromosome: 12 |
| Gene Name: apoptotic peptidase activating factor |
Number of products: 5 (alternatively spliced) |
| GI: 89161190 |
Number of PolyA signals: 1 |
| Gene length: 90134 nt. |
Aliases: CED4 |
| GenBank format: NC_000012.10 |
FASTA format: NC_000012.10 |
| Homologues:
452153, 482620, 11783, 78963, 417926 |
Status: Reviewed |
| Non-overlapping QGRS (30,2): 238 |
Overlapping QGRS (30,2): 4547 |
| Non-overlapping QGRS (45,3): 13 |
Overlapping QGRS (45,3): 159 |
Gene Ontology
• Function: ATP binding, caspase activator activity, nucleotide binding, protein binding
• Process: caspase activation via cytochrome c, nervous system development, regulation of apoptosis
• Component: cytosol, intracellular |
| Date submitted: 2006-04-16 23:26:29 |
Submitted by: Oleg Kikin |
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The gene has 5 known alternatively spliced RNA products
| Product #1: NM_181861.1 |
| Number of exons: 27 | Total # of QGRS: 235 |
| Number of introns: 26 | Total # of QGRS (including overlaps): 4548 |
| Number of poly-A signals: 1 | QGRS mapped near RNA processing sites: 0 |
Product map:   |
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| Product #2: NM_181868.1 |
| Number of exons: 26 | Total # of QGRS: 235 |
| Number of introns: 25 | Total # of QGRS (including overlaps): 4548 |
| Number of poly-A signals: 1 | QGRS mapped near RNA processing sites: 0 |
| Product map: |
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| Product #3: NM_181869.1 |
| Number of exons: 8 | Total # of QGRS: 239 |
| Number of introns: 7 | Total # of QGRS (including overlaps): 4556 |
| Number of poly-A signals: 1 | QGRS mapped near RNA processing sites: 0 |
| Product map: |
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| Product #4: NM_013229.2 |
| Number of exons: 27 | Total # of QGRS: 235 |
| Number of introns: 26 | Total # of QGRS (including overlaps): 4548 |
| Number of poly-A signals: 1 | QGRS mapped near RNA processing sites: 0 |
| Product map: |
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| Product #5: NM_001160.2 |
| Number of exons: 26 | Total # of QGRS: 235 |
| Number of introns: 25 | Total # of QGRS (including overlaps): 4548 |
| Number of poly-A signals: 1 | QGRS mapped near RNA processing sites: 0 |
| Product map: |
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